Transcriptomics and Proteomics

Transcriptomic studies measure the simultaneous expression of approximately thousands of genes and can be used to recognize which genes are up or down regulated under certain conditions. Metabolomic studies provide information on the metabolites found within a biological sample. These two branches seek to uncover the underlying systems biology and when combined they can be successful in predicting gene functions or identifying gene metabolite associations. Proteomics refers to study of large scale proteomes. Proteome is a set of proteins produced in an organism or biological environment. One of the Systems Biology’s important objectives is to understand the regulation of cell behavior. And important approaches involve are Measure of transcriptomic profiles through microarrays, RNA sequence etc. and measure of proteomic profiles through techniques such as gel electrophoresis and mass spectrometry.

  • Gene Expression Profiling and Epigenetics
  • Next generation sequencing (NGS) technologies
  • RNA-seq technology
  • Transcriptome and proteome analysis
  • RNAi gene silencing technology
  • Metabolomics and phytochemical genomics
  • Structural biology
  • Integration of proteomics and systems approaches
  • Signalling pathways
  • Identification of metabolites using high resolution

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