Metabolomics studies identifies metabolites for early diagnosis of disease. Obesity is becoming a major health concern in the world. Metabolic syndrome (MS) is a disease with complex pathological condition and pathogenesis involving multiple systems of the human body. Metabolomic syndrome is characterized with central obesity, hyperglycemia, hyperlipidemia, hypertension, hyperuricemia, and abnormal aggregation of other metabolic components . Metabolomics provides molecular information for understanding pathogenesis and has been playing an important role in unravelling the pathophysiology and identifying early biomarkers of specific physiological responses of complex human diseases in particular metabolomic syndrome.